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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 718116Generated: October 29, 2026

HCID 34176367, compound → 3-Phenyl-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyrazine

https://huagongshe.com/reaction/718116

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 34176367HCID 34176367—
ReactantHCID 178418361HCID 178418361—
CatalystPalladiumHCID 23938—
SolventEthanolHCID 702—
Product3-Phenyl-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyrazineHCID 34176360100.3%

Reaction Steps

Title compound 472 (310 mg, 1.34 mmol) was dissolved in EtOH (25 mL) and 10% Pd/C (75 mg, 25% w/w) was added. The reaction mixture was stirred under 1 atmosphere of hydrogen over night. The catalyst was filtered and the filtrate was evaporated to afford title compound 473 (269 mg, 100%). MS (m/z): 201.1 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09193749B2
Source datasetuspto-grants-2015_11
ORD IDord-c69ed56040004f348914d5c0e1fd9ee3
Source noteuspto-grants-2015_11