Trifluoroacetic acid → HCID 117728382, compound

Participants

Reaction Steps

To a solution of compound 19e (170 mg, 0.335 mmol) in DCM (2 mL), TFA (2 mL) was added. The resulting mixture was stirred at rt for 1 h and concentrated. The resulting residue was dried in vacuo for 4 h and suspended in ether. The mixture was concentrated and the resulting residue was dried in vacuo overnight to obtain ethyl 4-(6-(azetidin-3-yl)-4-morpholinopyrrolo[1,2-b]pyridazin-7-yl)benzoate trifluoro acetic acid salt (19g), which was used without further purification in the next step.

Provenance & Evidence