HRID718647

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：Brc1c(CCc2ccc3ccccc3n2)nc2c(N3CCOCC3)ccnn12

HCID117728694

未命名化合物

结构：Cn1nc(-c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)n(COCC[Si](C)(C)C)c1=O

HCID131734177

未命名化合物

PRODUCTS

生成物

结构：Cn1nc(-c2ccc(-c3c(CCc4ccc5ccccc5n4)nc4c(N5CCOCC5)ccnn34)cc2)n(COCC[Si](C)(C)C)c1=O

HCID123938244

未命名化合物

PROCEDURE

实验过程

Compound 46a was subjected to Suzuki coupling conditions with compound 51d as described in Example 38, Step A to obtain compound 51e as a light yellow solid. Mass Spectrum (LCMS, ESI pos.): Calcd. for C36H42N8O3Si: 663.3 (M+H). Found: 663.4.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-9304abbbab7c4374aa96150b1ff41b35
来源数据集: uspto-grants-2015_11
DOI: 10.6084/m9.figshare.5104873.v1
专利: US09193736B2
来源说明: uspto-grants-2015_11

反应 SMILES

Br[C:2]1[N:6]2[N:7]=[CH:8][CH:9]=[C:10]([N:11]3[CH2:16][CH2:15][O:14][CH2:13][CH2:12]3)[C:5]2=[N:4][C:3]=1[CH2:17][CH2:18][C:19]1[CH:28]=[CH:27][C:26]2[C:21](=[CH:22][CH:23]=[CH:24][CH:25]=2)[N:20]=1.[CH3:29][N:30]1[C:34](=[O:35])[N:33]([CH2:36][O:37][CH2:38][CH2:39][Si:40]([CH3:43])([CH3:42])[CH3:41])[C:32]([C:44]2[CH:49]=[CH:48][C:47](B3OC(C)(C)C(C)(C)O3)=[CH:46][CH:45]=2)=[N:31]1>>[CH3:29][N:30]1[C:34](=[O:35])[N:33]([CH2:36][O:37][CH2:38][CH2:39][Si:40]([CH3:43])([CH3:41])[CH3:42])[C:32]([C:44]2[CH:45]=[CH:46][C:47]([C:2]3[N:6]4[N:7]=[CH:8][CH:9]=[C:10]([N:11]5[CH2:16][CH2:15][O:14][CH2:13][CH2:12]5)[C:5]4=[N:4][C:3]=3[CH2:17][CH2:18][C:19]3[CH:28]=[CH:27][C:26]4[C:21](=[CH:22][CH:23]=[CH:24][CH:25]=4)[N:20]=3)=[CH:48][CH:49]=2)=[N:31]1