HRID718656

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：Brc1c(CCc2ccc3ccccc3n2)nc2c(N3CCOCC3)ccnn12

HCID117728694

未命名化合物

结构：CC1(C)OB(c2ccc(-n3nnn(COCC[Si](C)(C)C)c3=O)cc2)OC1(C)C

HCID131734179

未命名化合物

PRODUCTS

生成物

结构：C[Si](C)(C)CCOCn1nnn(-c2ccc(-c3c(CCc4ccc5ccccc5n4)nc4c(N5CCOCC5)ccnn34)cc2)c1=O

HCID123932123

未命名化合物

PROCEDURE

实验过程

Compound 46a (0.30 g, 0.68 mmol) was subjected to Suzuki coupling conditions with compound 53c using the procedures described in Example 38, Step A to obtain compound 53d as a white solid. Mass Spectrum (LCMS, ESI pos.): Calcd. for C34H39N9O3Si: 650.3 (M+H). Found: 650.2.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-a43f893c8cfa4ad98b4bbbb623f257c2
来源数据集: uspto-grants-2015_11
DOI: 10.6084/m9.figshare.5104873.v1
专利: US09193736B2
来源说明: uspto-grants-2015_11

反应 SMILES

Br[C:2]1[N:6]2[N:7]=[CH:8][CH:9]=[C:10]([N:11]3[CH2:16][CH2:15][O:14][CH2:13][CH2:12]3)[C:5]2=[N:4][C:3]=1[CH2:17][CH2:18][C:19]1[CH:28]=[CH:27][C:26]2[C:21](=[CH:22][CH:23]=[CH:24][CH:25]=2)[N:20]=1.CC1(C)C(C)(C)OB([C:37]2[CH:42]=[CH:41][C:40]([N:43]3[C:47](=[O:48])[N:46]([CH2:49][O:50][CH2:51][CH2:52][Si:53]([CH3:56])([CH3:55])[CH3:54])[N:45]=[N:44]3)=[CH:39][CH:38]=2)O1>>[O:14]1[CH2:15][CH2:16][N:11]([C:10]2[C:5]3[N:6]([C:2]([C:37]4[CH:42]=[CH:41][C:40]([N:43]5[C:47](=[O:48])[N:46]([CH2:49][O:50][CH2:51][CH2:52][Si:53]([CH3:56])([CH3:55])[CH3:54])[N:45]=[N:44]5)=[CH:39][CH:38]=4)=[C:3]([CH2:17][CH2:18][C:19]4[CH:28]=[CH:27][C:26]5[C:21](=[CH:22][CH:23]=[CH:24][CH:25]=5)[N:20]=4)[N:4]=3)[N:7]=[CH:8][CH:9]=2)[CH2:12][CH2:13]1