HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Bromoanisole → 3-(3-Methoxyphenyl)-8-morpholinoimidazo[1,2-b]pyridazine-2-carbaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Bromoanisole | HCID 16971 | — |
| Reactant | 8-Morpholinoimidazo[1,2-b]pyridazine-2-carbaldehyde | HCID 117728638 | — |
| Product | 3-(3-Methoxyphenyl)-8-morpholinoimidazo[1,2-b]pyridazine-2-carbaldehyde | HCID 117728310 | — |
Reaction Steps
Compound 5e (162 mg, 0.698 mmol) was coupled with 3-bromoanisole (0.13 mL, 1.04 mmol) according to the procedures described in Example 20, Step A to obtain compound 77a. Mass spectrum (LCMS, ESI pos.) Calcd. For C18H18N4O3 339.1 (M+H). found 339.2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09193736B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-89a8a04edfb54799b7bec3c0ff7598d9 |
| Source note | uspto-grants-2015_11 |