HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lithium hydroxide, monohydrate → 2-(2-(Benzylcarbamoyl)-1-methylhydrazinyl)acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lithium hydroxide, monohydrate | HCID 168937 | — |
| Reactant | Ethyl 2-(1-allyl-2-(benzylcarbamoyl)hydrazinyl)acetate | HCID 59541461 | — |
| Product | 2-(2-(Benzylcarbamoyl)-1-methylhydrazinyl)acetic acid | HCID 53397489 | 88.5% |
Reaction Steps
According to the procedure described in the synthesis method of Compound VI-2 with the modification that the reaction was carried out overnight, ethyl 2-(1-allyl-2-(benzylcarbamoyl)hydrazinyl)acetate (Compound V-2) 1.33 g (5.0 mmol) was reacted with lithium hydroxide monohydrate 420 mg (10.0 mmol) to obtain the title compound 1.05 g (88%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09193734B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-34be39171bbe46d381f393b19a0e2ba8 |
| Source note | uspto-grants-2015_11 |