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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 719136Generated: October 29, 2026

HCID 21896882, compound → HCID 178440011, compound

https://huagongshe.com/reaction/719136

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 21896882HCID 21896882—
Reactant1-(4-Chloro-phenyl)-pentane-1,2-diamineHCID 21896886—
Reactant5-(4-chloro-phenyl)-4-cyclopentylmethyl-2-(2-ethoxy-4-methoxy-phenyl)-4,5-dihydro-1H-imidazoleHCID 178467016—
ProductHCID 178440011HCID 178440011—

Reaction Steps

5-(4-Chloro-phenyl)-2-(2-ethoxy-4-methoxy-phenyl)-4-propyl-4,5-dihydro-1H-imidazole was prepared from 1-(4-chloro-phenyl)-pentane-1,2-diamine and ethyl 2-ethoxy-4-methoxy-benzimidate hydrochloride in an analogous manner as described for the preparation of 5-(4-chloro-phenyl)-4-cyclopentylmethyl-2-(2-ethoxy-4-methoxy-phenyl)-4,5-dihydro-1H-imidazole (Example 9). HR-MS (ES, m/z) observed 373.1680, calculated for C21H26N2O2Cl [(M+H)+]373.1678.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07132421B2
Source datasetuspto-grants-2006_11
ORD IDord-31ebf4501c824ded83c39e6927473d63
Source noteuspto-grants-2006_11