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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 719150Generated: October 30, 2026

[5-(4-Chloro-phenyl)-4-cyclopentylmethyl-2-(2-ethoxy-4-methoxy-phenyl)-4,5-dihydro-imidazol-1-yl]-(4-methyl-piperazin-1-yl)-methanone → HCID 11490110, compound

https://huagongshe.com/reaction/719150

Reaction equation

Participants

RoleNameHCIDCharge
Reactant[5-(4-Chloro-phenyl)-4-cyclopentylmethyl-2-(2-ethoxy-4-methoxy-phenyl)-4,5-dihydro-imidazol-1-yl]-(4-methyl-piperazin-1-yl)-methanoneHCID 11193096—
ReactantHCID 178467014HCID 178467014—
ProductHCID 11490110HCID 11490110—

Reaction Steps

[5-(4-Chloro-phenyl)-4-cyclopentyl-2-(2-ethoxy-4-methoxy-phenyl)-4,5-dihydro-imidazol-1-yl]-(4-pyrrolidin-1-yl-piperidin-1-yl)-methanone was prepared from 5-(4-chloro-phenyl)-4-cyclopentyl-2-(2-ethoxy-4-methoxy-phenyl)-4,5-dihydro-1H-imidazole, trifluoroacetate salt (Example 19) in an analogous manner as described for the preparation of [5-(4-chloro-phenyl)-4-cyclopentylmethyl-2-(2-ethoxy-4-methoxy-phenyl)-4,5-dihydro-imidazol-1-yl]-(4-methyl-piperazin-1-yl)-methanone (Example 24). HR-MS (ES, m/z) observed 579.3104, calculated for C33H44N4O3Cl [(M+H)+]579.3097.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07132421B2
Source datasetuspto-grants-2006_11
ORD IDord-0c5d7845e11e4ce7a87f43bb7fac2e6d
Source noteuspto-grants-2006_11