1-Methoxycarbonyl-2-isopropylidene hydrazine → Methyl 2-isopropylhydrazinecarboxylate

HRID 71920Notes

Reaction equation

HRID 71920 reaction equation
[CH3:1][O:2][C:3]([NH:5][N:6]=[C:7]([CH3:9])[CH3:8])=[O:4]>C(O)C.C(O)(=O)C.O=[Pt]=O>[CH3:1][O:2][C:3]([NH:5][NH:6][CH:7]([CH3:9])[CH3:8])=[O:4]

Participants

5

Reactant 1

HCID 9095211-Methoxycarbonyl-2-isopropylidene hydrazine

Product 1

HCID 57863323Methyl 2-isopropylhydrazinecarboxylateYield 77.6%

Reagents, catalysts & solvents 3

HCID 345198Adams' catalystCatalystHCID 176Acetic AcidSolventHCID 702EthanolSolvent

Procedure

N′-Isopropylidene-hydrazine-carboxylic acid methyl ester (6.45 g) were dissolved in ethanol (50 mL) and acetic acid (50 mL). PtO2 (0.231 g) was added, and reaction was stirred at room temperature for 22 hours under an atmosphere of hydrogen. Mixture was evaporated under vacuum, giving N′-Isopropyl-hydrazine-carboxylic acid methyl ester (5.08 g, 77%) as a white solid.

Workup

  1. customreaction
  2. customMixture was evaporated under vacuum

Sources & evidence

ORD record
ord-449bd75241284b089e5edaa9a4e0adbe
Source dataset
uspto-grants-2014_09
Patent number
US08822430B2

Reaction notes

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