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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 719319Generated: October 27, 2026

N-(4-(2-Amino-1,3-thiazol-4-yl)phenyl)acetamide → N-[4-(2-{[(4-propylphenyl)sulfonyl]amino}-1,3-thiazol-4-yl)phenyl]acetamide

https://huagongshe.com/reaction/719319

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-(4-(2-Amino-1,3-thiazol-4-yl)phenyl)acetamideHCID 519881—
Reactant4-N-Propylbenzenesulphonyl chlorideHCID 2737222—
ProductN-[4-(2-{[(4-propylphenyl)sulfonyl]amino}-1,3-thiazol-4-yl)phenyl]acetamideHCID 8504637—

Reaction Steps

The title compound was prepared from N-[4-(2-amino-1,3-thiazol-4-yl)phenyl]acetamide and 4-n-propylbenzenesulfonyl chloride as described in the synthetic METHOD B to give a yellow solid (1.0 mg) with purity >80%. MS (pos) m/z 416.2.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07132436B2
Source datasetuspto-grants-2006_11
ORD IDord-6e1cd245a7844984bb3d46c1f4e9c52b
Source noteuspto-grants-2006_11