HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Chloro-2-methylbenzenesulfonyl chloride → 3-Chloro-N-(7-methoxy-4,5-dihydronaphtho[1,2-d][1,3]thiazol-2-yl)-2-methylbenzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Chloro-2-methylbenzenesulfonyl chloride | HCID 522734 | — |
| Reactant | 7-Methoxy-4,5-dihydronaphtho[1,2-d][1,3]thiazol-2-amine hydrobromide | HCID 2807473 | — |
| Product | 3-Chloro-N-(7-methoxy-4,5-dihydronaphtho[1,2-d][1,3]thiazol-2-yl)-2-methylbenzenesulfonamide | HCID 10295687 | — |
Reaction Steps
The title compound was prepared from 7-methoxy-4,5-dihydronaphto[1,2-D][1,3]thiazol-2-amine hydrobromide and 3-chloro-2-methylbenzenesulfonyl chloride as described in the synthetic METHOD B to give a white solid (30.7 mg) with purity >90%. MS (pos) m/z 421.1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07132436B2 |
| Source dataset | uspto-grants-2006_11 |
| ORD ID | ord-2d9575272ad5423ab484eb46751c350f |
| Source note | uspto-grants-2006_11 |