HuagongsheHuagongshe Chemistry Print Report · For research reference only
(1,1'-Biphenyl)-4-sulphonyl chloride → N-(4-{2-[([1,1'-biphenyl]-4-ylsulfonyl)amino]-1,3-thiazol-4-yl}phenyl)acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (1,1'-Biphenyl)-4-sulphonyl chloride | HCID 74192 | — |
| Reactant | N-(4-(2-Amino-1,3-thiazol-4-yl)phenyl)acetamide | HCID 519881 | — |
| Product | N-(4-{2-[([1,1'-biphenyl]-4-ylsulfonyl)amino]-1,3-thiazol-4-yl}phenyl)acetamide | HCID 10182341 | — |
Reaction Steps
The title compound was prepared N-[4-(2-amino-1,3 -thiazol-4-yl)phenyl]acetamide and 4-phenylbenzenesulfonyl chloride as described in the synthetic METHOD B to give a white-yellow solid (8.6 mg) with purity >80%. MS (pos) m/z 450.3.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07132436B2 |
| Source dataset | uspto-grants-2006_11 |
| ORD ID | ord-5cca1f59d5f6406899ceb6fd157bdb1d |
| Source note | uspto-grants-2006_11 |