HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(3-Chloro-2-thienyl)-1,3-thiazol-2-amine → 2,4-Dichloro-N-[4-(3-chloro-2-thienyl)1,3-thiazol-2-yl]-6-methylbenzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(3-Chloro-2-thienyl)-1,3-thiazol-2-amine | HCID 1488441 | — |
| Reactant | 2,4-Dichloro-6-methylbenzenesulfonyl chloride | HCID 2801387 | — |
| Product | 2,4-Dichloro-N-[4-(3-chloro-2-thienyl)1,3-thiazol-2-yl]-6-methylbenzenesulfonamide | HCID 10274951 | — |
Reaction Steps
The title compound was prepared from 4-(3-chloro-2-thienyl)-1,3-thiazol-2-amine and 2,4-dichloro-6-methylbenzenesulfonyl chloride as described in the synthetic METHOD B to give a yellow solid (9.4 mg) with purity >90%: MS (pos) m/z 439.1, 441.1; HRS m/z 437.8875 (calc. of monoisotopic mass for C14H9Cl3N2O2S3 gives 437.8892).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07132436B2 |
| Source dataset | uspto-grants-2006_11 |
| ORD ID | ord-146beaaec28f47d2b1d038b40ab60e58 |
| Source note | uspto-grants-2006_11 |