HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,4,5-Trichlorobenzenesulfonyl chloride → 2,4,5-Trichloro-N-[4-(3-chloro-2-thienyl)-1,3-thiazol-2-yl]benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,4,5-Trichlorobenzenesulfonyl chloride | HCID 27575 | — |
| Reactant | 4-(3-Chloro-2-thienyl)-1,3-thiazol-2-amine | HCID 1488441 | — |
| Product | 2,4,5-Trichloro-N-[4-(3-chloro-2-thienyl)-1,3-thiazol-2-yl]benzenesulfonamide | HCID 10161650 | — |
Reaction Steps
The title compound was prepared from 4-(3-chloro-2-thienyl)-1,3-thiazol-2-amine (59 mg) and 2,4,5-trichlorobenzenesulfonyl chloride (76 mg) as described in the synthetic METHOD B to give a white solid (9.2 mg) with purity >90%: MS (pos) m/z 459.2, 461.2, 463.2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07132436B2 |
| Source dataset | uspto-grants-2006_11 |
| ORD ID | ord-7ad6317c35944b9c939b3c1ecb08240f |
| Source note | uspto-grants-2006_11 |