HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4,5-Dichlorothiophene-2-sulfonyl chloride → 4,5-Dichloro-N-(7-methoxy-4,5-dihydronaphtho[1,2-d][1,3]thiazol-2-yl)-2-thiophenesulfonamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4,5-Dichlorothiophene-2-sulfonyl chloride | HCID 518622 | — |
| Edukt | 7-Methoxy-4,5-dihydronaphtho[1,2-d][1,3]thiazol-2-amine hydrobromide | HCID 2807473 | — |
| Produkt | 4,5-Dichloro-N-(7-methoxy-4,5-dihydronaphtho[1,2-d][1,3]thiazol-2-yl)-2-thiophenesulfonamide | HCID 10114591 | — |
Reaktionsschritte
The title compound was prepared from 7-methoxy-4,5-dihydronaphtho(1,2-D)(1,3)thiazol-2-amine hydrobromide (85 mg) and 2,3-dichlorothiophene-5-sulfonyl chloride (68 mg) as described in the synthetic METHOD B to give a white solid (16.4 mg) with purity >90%: MS (pos) m/z 447.3, 449.3.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07132436B2 |
| Quelldatensatz | uspto-grants-2006_11 |
| ORD ID | ord-fa79ddbdd8ca4e5193324f5720e8f7c1 |
| Quellennotiz | uspto-grants-2006_11 |