HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,4,5-Trichlorobenzenesulfonyl chloride → N-[4-(2-{[(2,4,5-Trichlorophenyl)sulfonyl]amino}-1,3-thiazol-4-yl)phenyl]acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,4,5-Trichlorobenzenesulfonyl chloride | HCID 27575 | — |
| Reactant | N-(4-(2-Amino-1,3-thiazol-4-yl)phenyl)acetamide | HCID 519881 | — |
| Product | N-[4-(2-{[(2,4,5-Trichlorophenyl)sulfonyl]amino}-1,3-thiazol-4-yl)phenyl]acetamide | HCID 10277267 | — |
Reaction Steps
The title compound was prepared from N-[4-(2-amino-1,3-thiazol-4-yl)phenyl]acetamide (63 mg) and 2,4,5-trichlorobenzenesulfonyl chloride (76 mg) as described in the synthetic METHOD B to give a white-yellow solid (5,0 mg) with purity >90%: MS (pos) m/z 476.3. 478.3.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07132436B2 |
| Source dataset | uspto-grants-2006_11 |
| ORD ID | ord-d99c75a2a297400f8780e70a4160c1a1 |
| Source note | uspto-grants-2006_11 |