Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-Bromo-5-chlorothiophene-2-sulfonyl chloride → 3-Bromo-5-chloro-N-(7-methoxy-4,5-dihydronaphtho[1,2-d][1,3]thiazol-2-yl)-2-thiophenesulfonamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-Bromo-5-chlorothiophene-2-sulfonyl chloride | HCID 2737400 | — |
| 반응물 | 7-Methoxy-4,5-dihydronaphtho[1,2-d][1,3]thiazol-2-amine hydrobromide | HCID 2807473 | — |
| 생성물 | 3-Bromo-5-chloro-N-(7-methoxy-4,5-dihydronaphtho[1,2-d][1,3]thiazol-2-yl)-2-thiophenesulfonamide | HCID 10163539 | — |
반응 단계
The title compound was prepared 7-methoxy-4,5-dihydronaphtho(1,2-D)(1,3)thiazol-2-amine hydrobromide (85 mg) and 3-bromo-5-chlorothiophene-2-sulfonyl chloride (80 mg) as described in the synthetic METHOD B to give a white solid (17.8 mg) with purity >80%: MS (pos) m/z 491.3, 493.3.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07132436B2 |
| 출처 데이터셋 | uspto-grants-2006_11 |
| ORD ID | ord-539256eb67a9429590a9b69e8d4f7a16 |
| 출처 메모 | uspto-grants-2006_11 |