Benzenesulfonyl chloride → HCID 11429136, compound

HRID 719376Notes

Reaction equation

[N+:1]([C:4]1[CH:17]=[C:16]2[C:7]([CH2:8][CH2:9][C:10]3[S:14][C:13]([NH2:15])=[N:12][C:11]=32)=[CH:6][CH:5]=1)([O-:3])=[O:2].[C:18]1([S:24](Cl)(=[O:26])=[O:25])[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1>>[N+:1]([C:4]1[CH:17]=[C:16]2[C:7]([CH2:8][CH2:9][C:10]3[S:14][C:13]([NH:15][S:24]([C:18]4[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=4)(=[O:26])=[O:25])=[N:12][C:11]=32)=[CH:6][CH:5]=1)([O-:3])=[O:2]

Participants

Reactant 2

HCID 7369Benzenesulfonyl chloride

HCID 9992165HCID 9992165, compound

Product 1

HCID 11429136HCID 11429136, compound

Procedure

The title compound was prepared from 8-nitro-4,5-dihydronaphtho[1,2-d][1,3]thiazol-2-amine (100 mg, synthesized according to METHOD I from 7-nitrotetralone) and benzenesulfonyl chloride (85 mg) as described in the synthetic METHOD A to give a yellow powder (12 mg) with a purity of >90%: MS-ES (neg) m/z 386.3.

Sources & evidence

ORD record: ord-97e59e794b3e402c9429913e4af03c55
Source dataset: uspto-grants-2006_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07132436B2

Reaction notes

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