Ethanol → HCID 21896917, compound

HRID 719444Notes

Reaction equation

HRID 719444 reaction equation
Cl[C:2]1[N:7]=[C:6]([NH:8][C:9]2[CH:14]=[CH:13][C:12]([O:15][CH3:16])=[C:11]([Cl:17])[CH:10]=2)[N:5]=[C:4]([NH:18][CH:19]2[CH2:25][CH2:24][CH2:23][CH2:22][CH2:21][CH2:20]2)[N:3]=1.C([O-])([O-])=O.[K+].[K+].[CH2:32]([OH:34])[CH3:33]>>[CH2:32]([O:34][C:2]1[N:7]=[C:6]([NH:8][C:9]2[CH:14]=[CH:13][C:12]([O:15][CH3:16])=[C:11]([Cl:17])[CH:10]=2)[N:5]=[C:4]([NH:18][CH:19]2[CH2:25][CH2:24][CH2:23][CH2:22][CH2:21][CH2:20]2)[N:3]=1)[CH3:33]

Participants

4

Reactant 3

HCID 702EthanolHCID 11430Potassium CarbonateHCID 218970216-chloro-N-(3-chloro-4-methoxyphenyl)-N'-cycloheptyl-[1,3,5]triazine-2,4-diamine

Product 1

HCID 21896917HCID 21896917, compound

Procedure

A portion of 6-chloro-N-(3-chloro-4-methoxyphenyl)-N′-cycloheptyl-[1,3,5]triazine-2,4-diamine (5 g) was refluxed in ethanol in presence of K2CO3 (3.2 g) for about 8–10 h. TLC was monitored. After the completion of the reaction, the reaction mass was filtered through vacuum and the filtrate was evaporated to yield the title compound. (Wt. 4.6 g Y: 90%).

Workup

  1. customAfter the completion of the reaction
  2. filtrationthe reaction mass was filtered through vacuum
  3. customthe filtrate was evaporated

Sources & evidence

ORD record
ord-8198241d38894d87adc3bceeeb0f121d
Source dataset
uspto-grants-2006_11
Patent number
US07132423B2

Reaction notes

Loading…