Oxalic Acid → HCID 10347574, compound

HRID 719681Notes

Reaction equation

HRID 719681 reaction equation
[C:1]([OH:6])(=[O:5])[C:2]([OH:4])=[O:3].[CH3:7][N:8]([CH3:39])[CH2:9][CH2:10][CH2:11][CH2:12][NH:13][C:14]([C:16]1[CH:17]=[C:18]([C:22]2[CH:27]=[CH:26][C:25]([CH2:28][S:29][CH2:30][CH2:31][O:32][C:33]3[CH:38]=[CH:37][CH:36]=[CH:35][CH:34]=3)=[CH:24][CH:23]=2)[CH:19]=[CH:20][CH:21]=1)=[O:15]>CCOC(C)=O>[C:1]([OH:6])(=[O:5])[C:2]([OH:4])=[O:3].[CH3:39][N:8]([CH3:7])[CH2:9][CH2:10][CH2:11][CH2:12][NH:13][C:14]([C:16]1[CH:17]=[C:18]([C:22]2[CH:27]=[CH:26][C:25]([CH2:28][S:29][CH2:30][CH2:31][O:32][C:33]3[CH:34]=[CH:35][CH:36]=[CH:37][CH:38]=3)=[CH:24][CH:23]=2)[CH:19]=[CH:20][CH:21]=1)=[O:15]

Participants

4

Reactant 2

HCID 971Oxalic AcidHCID 10347575HCID 10347575, compound

Product 1

HCID 10347574HCID 10347574, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

The product was converted to the oxalate salt by adding solid oxalic acid (0.15 g) to an EtOAc solution of 4′-(2-phenoxy-ethylsulfanylmethyl)-biphenyl-3-carboxylic acid (4-dimethylamino-butyl)-amide giving 4′-(2-phenoxy-ethylsulfanylmethyl)-biphenyl-3-carboxylic acid (4-dimethylamino-butyl)-amide oxalate (0.4129 g) as a white solid.

Sources & evidence

ORD record
ord-651b65937e4a4a70aa266e6529f15a26
Source dataset
uspto-grants-2006_11
Patent number
US07132456B2

Reaction notes

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