HCID 86595355, compound → HCID 86595356, compound

HRID 719740Notes

Reaction equation

HRID 719740 reaction equation
[Cl-:1].[CH3:2][N+:3]1[CH:7]=[CH:6][N:5]([CH2:8][CH:9]2[CH2:13][CH2:12][CH2:11][N:10]2[C:14]2[CH:19]=[CH:18][C:17]([N+:20]([O-])=O)=[CH:16][CH:15]=2)[CH:4]=1>C(O)C.[Pd]>[ClH:1].[Cl-:1].[NH2:20][C:17]1[CH:18]=[CH:19][C:14]([N:10]2[CH2:11][CH2:12][CH2:13][CH:9]2[CH2:8][N:5]2[CH:6]=[CH:7][N+:3]([CH3:2])=[CH:4]2)=[CH:15][CH:16]=1

Participants

4

Reactant 1

HCID 86595355HCID 86595355, compound

Product 1

HCID 86595356HCID 86595356, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

3 g (0.093 mol) of 1-methyl-3-[1-(4-nitrophenyl)pyrrolidin-2-ylmethyl]-3H-imidazol-1-ium (2) dissolved in 350 ml of ethanol were hydrogenated in the presence of palladium-on-charcoal under a hydrogen pressure of 10 bar at a temperature of 30° C.; after filtering off the catalyst, the expected derivative (3) was isolated in the form of the hydrochloride. 2.6 g of a white powder were obtained.

Workup

  1. customat a temperature of 30° C.
  2. filtrationafter filtering off the catalyst

Sources & evidence

ORD record
ord-002f2343ffa64d27b57423481489db5b
Source dataset
uspto-grants-2006_11
Patent number
US07132543B2

Reaction notes

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