2-Hydroxy benzimidazole → HCID 21887473, compound

HRID 719773Notes

Reaction equation

HRID 719773 reaction equation
[NH:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[NH:3][C:2]1=[O:10].[Cl:11][CH2:12][CH2:13][CH2:14][CH2:15][C:16](Cl)=[O:17]>>[Cl:11][CH2:12][CH2:13][CH2:14][CH2:15][C:16]([C:8]1[CH:7]=[CH:6][C:5]2[NH:1][C:2](=[O:10])[NH:3][C:4]=2[CH:9]=1)=[O:17]

Participants

3

Reactant 2

HCID 119852-Hydroxy benzimidazoleHCID 740895-Chlorovaleryl chloride

Product 1

HCID 21887473HCID 21887473, compoundYield 57.9%

Procedure

Using 1,3-dihydro-2H-benzimidazol-2-one (4.00 g) and 5-chlorovaleryl chloride (9.24 g) according to the same method as that of Reference Example 1, the title compound (4.36 g) was obtained as colorless crystals.

Sources & evidence

ORD record
ord-b722e5783daa4d5d990164dfe0aebdd1
Source dataset
uspto-grants-2006_11
Patent number
US07132547B2

Reaction notes

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