HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methacryloyl chloride → N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methylprop-2-enamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methacryloyl chloride | HCID 13528 | — |
| Reactant | 4-Amino-2-(trifluoromethyl)benzonitrile | HCID 522170 | — |
| Product | N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methylprop-2-enamide | HCID 11149469 | — |
Reaction Steps
Using 4-cyano-3-trifluoromethylaniline and methacryloyl chloride as starting materials, the title compound is prepared according to the method described in J. Med. Chem., 1988, 954–959.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07132560B2 |
| Source dataset | uspto-grants-2006_11 |
| ORD ID | ord-1957e7558bbf4f8aa9d0d0efc30570f5 |
| Source note | uspto-grants-2006_11 |