反应详情

1-(3a,6a-Dihydro-thieno[3,2-b]thiophen-2-yl)-ethanone (453 mg, 2.48 mmol) was dissolved in THF (12 mL) and phenyltrimethylammonium tribromide (932 mg, 2.48 mmol) was added. After stirring for 1 h, the suspension was filtered over CELITE. The filtrate was diluted with diethyl ether, then washed with saturated aqueous NaHCO3 and brine then dried over MgSO4, filtered and concentrated to afford the title compound which was carried on without purification.

1. filtrationthe suspension was filtered over CELITE
2. additionThe filtrate was diluted with diethyl ether
3. washwashed with saturated aqueous NaHCO3 and brine
4. dry with materialthen dried over MgSO4
5. filtrationfiltered
6. concentrationconcentrated