HCID 67482685, compound → HCID 21897377, compound

Participants

Reaction Steps

A solution of 5-(2,2-dimethoxy-ethyl)-pyrazin-2-yl-carbamic acid benzyl ester (130 mg, 0.4096 mmol) in methanol (5 mL) was treated with 10% palladium on activated carbon (30 mg). The reaction mixture was then hydrogenated under a hydrogen atmosphere at 25° C. and atmospheric pressure for 60 min, The mixture was filtered through celite, and the filtrate was concentrated in vacuo to afford 5-(2,2-dimethoxy-ethyl)-pyrazin-2-ylamine (75 mg, 100%) as a pale yellow oil.

Provenance & Evidence