Piperazine → HCID 21891660, compound

HRID 720364Notes

Reaction equation

HRID 720364 reaction equation
Cl[CH2:2][C:3]1[O:4][C:5]2[C:11]([O:12][CH3:13])=[C:10]([O:14][CH3:15])[C:9]([O:16][CH3:17])=[CH:8][C:6]=2[N:7]=1.[NH:18]1[CH2:23][CH2:22][NH:21][CH2:20][CH2:19]1>>[CH3:17][O:16][C:9]1[C:10]([O:14][CH3:15])=[C:11]([O:12][CH3:13])[C:5]2[O:4][C:3]([CH2:2][N:18]3[CH2:23][CH2:22][N:21]([CH2:2][C:3]4[O:4][C:5]5[C:11]([O:12][CH3:13])=[C:10]([O:14][CH3:15])[C:9]([O:16][CH3:17])=[CH:8][C:6]=5[N:7]=4)[CH2:20][CH2:19]3)=[N:7][C:6]=2[CH:8]=1

Participants

3

Reactant 2

HCID 4837PiperazineHCID 21891587HCID 21891587, compound

Product 1

HCID 21891660HCID 21891660, compound

Procedure

2-Chloromethyl-5,6,7-trimethoxybenzoxazole (156 mg) and piperazine (23 mg) were reacted in the same manner as in Example 1 to obtain the title compound as a free base.

Sources & evidence

ORD record
ord-c29273811c36490cb2e6e7cab79bbee9
Source dataset
uspto-grants-2006_11
Patent number
US07135473B2

Reaction notes

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