Piperazine → HCID 21892117, compound

Participants

Reaction Steps

The title compound was prepared as described for Example 21, using 3-cyano-(4-fluoro-benzoyl)-pyrrolo[1,2-a]quinoline ( 58 mg, 0.185 mmol) and piperazine (102 mg, 1.18 mmol), and yielded 57.2 mg (81%). 1H NMR (CDCl3): 8.01 (m, 3H), 7.80 (dd, J=7.8, 1.8 Hz, 1H), 7.64 (s, 2H), 7.52 (m, 2H), 7.34 (d, J=0.6 Hz, 1H), 6.60 (d, J=9.0 Hz, 2H), 3.41 (t, J=5.1 Hz, 4H 3.06 (t, J=4.5 Hz, 4H).

Provenance & Evidence