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HRID720455

反应详情

EQUATION

反应方程式

HRID 720455 的结构方程式

REACTANTS

反应物

2
结构：CN=C=O
HCID12228

Methyl isocyanate

C2H3NO

结构：N#Cc1c(N)nc(SCCN)c(C#N)c1-c1ccc(O)cc1
HCID135828224

未命名化合物

PRODUCTS

生成物

1
结构：CNC(=O)NCCSc1nc(N)c(C#N)c(-c2ccc(O)cc2)c1C#N
HCID135828227

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CN(C)C=O
溶剂HCID6228

N,N-Dimethylformamide

C3H7NO

PROCEDURE

实验过程

62.2 mg (0.2 mmol) of 2-amino-6-[(2-aminoethyl)sulfanyl]-4-(4-hydroxyphenyl)-3,5-pyridinedicarbonitrile are suspended in 0.4 ml of DMF, and 11.4 mg (0.2 mmol) of methyl isocyanate are added at room temperature. The mixture is stirred overnight, filtered and purified by preparative HPLC.

WORKUP

后处理

  1. filtrationfiltered
  2. custompurified by preparative HPLC