HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lithium borohydride → HCID 10005328, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lithium borohydride | HCID 4148881 | — |
| Reactant | HCID 11755954 | HCID 11755954 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 10005328 | HCID 10005328 | — |
Reaction Steps
Prepared by the reduction of 4-[8-(4-acetylamino-benzyl)-1-(2-fluorobenzyl)-2,6-dioxo-1,2,6,7-tetrahydro-purin-3-yl]-butyric acid methyl ester with lithium borohydride in tetrahydrofuran. The product was purified by chromatography on silica gel eluted with 9:1 chloroform/methanol. MS, m/z(M+)=479.1967.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07135475B2 |
| Source dataset | uspto-grants-2006_11 |
| ORD ID | ord-4033145014c24aeb97ec84a5f91311d2 |
| Source note | uspto-grants-2006_11 |