Lithium borohydride → HCID 10345501, compound

HRID 720619Notes

Reaction equation

HRID 720619 reaction equation
C[O:2][C:3]([CH:5]1[CH2:7][CH:6]1[CH2:8][N:9]1[C:17]2[N:16]=[C:15]([CH2:18][C:19]3[CH:24]=[CH:23][C:22]([NH:25][C:26](=[O:28])[CH3:27])=[CH:21][CH:20]=3)[NH:14][C:13]=2[C:12](=[O:29])[N:11]([CH2:30][C:31]2[CH:36]=[CH:35][CH:34]=[CH:33][C:32]=2[F:37])[C:10]1=[O:38])=O.[BH4-].[Li+]>O1CCCC1>[F:37][C:32]1[CH:33]=[CH:34][CH:35]=[CH:36][C:31]=1[CH2:30][N:11]1[C:12](=[O:29])[C:13]2[NH:14][C:15]([CH2:18][C:19]3[CH:20]=[CH:21][C:22]([NH:25][C:26](=[O:28])[CH3:27])=[CH:23][CH:24]=3)=[N:16][C:17]=2[N:9]([CH2:8][CH:6]2[CH2:7][CH:5]2[CH2:3][OH:2])[C:10]1=[O:38]

Participants

4

Reactant 2

HCID 4148881Lithium borohydrideHCID 10324351HCID 10324351, compound

Product 1

HCID 10345501HCID 10345501, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

This compound was prepared by the reduction of 2-[8-(4-acetylamino-benzyl)-1-(2-fluorobenzyl)-2,6-dioxo-1,2,6,7-tetrahydro-purin-3-ylmethyl]-cyclopropanecarboxylic acid methyl ester with lithium borohydride in tetrahydrofuran. MS, m/z(M+)=491.1966.

Sources & evidence

ORD record
ord-2deb5d7437bc41c2a11b0af426d2ae3c
Source dataset
uspto-grants-2006_11
Patent number
US07135475B2

Reaction notes

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