Cyclopropylamine → 2-chloro-N-cyclopropylbenzo[d]thiazole-6-carboxamide

HRID 72141Notes

Reaction equation

HRID 72141 reaction equation

[Cl:1][C:2]1[S:3][C:4]2[CH:10]=[C:9]([C:11]([OH:13])=O)[CH:8]=[CH:7][C:5]=2[N:6]=1.[CH:14]1([NH2:17])[CH2:16][CH2:15]1>C(Cl)CCl>[Cl:1][C:2]1[S:3][C:4]2[CH:10]=[C:9]([C:11]([NH:17][CH:14]3[CH2:16][CH2:15]3)=[O:13])[CH:8]=[CH:7][C:5]=2[N:6]=1

Participants

4

Reactant 2

HCID 69828Cyclopropylamine

HCID 185115842-Chloro-1,3-benzothiazole-6-carboxylic acid

Product 1

HCID 668836592-chloro-N-cyclopropylbenzo[d]thiazole-6-carboxamide

Reagents, catalysts & solvents 1

HCID 111,2-DichloroethaneSolvent

Procedure

2-chloro-N-cyclopropylbenzo[d]thiazole-6-carboxamide was prepared by EDC coupling of 2-chlorobenzo[d]thiazole-6-carboxylic acid and cyclopropylamine.

Sources & evidence

ORD record: ord-438384ae9844421e969f5ad5cf8bf913
Source dataset: uspto-grants-2014_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08828985B2

Reaction notes

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