HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclopentanecarboxylic acid, 2-oxo-, methyl ester → HCID 178517488, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclopentanecarboxylic acid, 2-oxo-, methyl ester | HCID 66328 | — |
| Reactant | 4-Chlorobenzene-1-carboximidamide hydrochloride | HCID 203436 | — |
| Reactant | Potassium tert-butoxide | HCID 23665647 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 178517488 | HCID 178517488 | — |
Reaction Steps
7.1 g of methyl 2-oxocyclopentane-1-carboxylate and 9.6 g of 4-chlorobenz-amidine hydrochloride were introduced into 50 ml of methanol. 5.6 g of potassium tert-butoxide were added with stirring. The reaction mixture was stirred under reflux for 4 hours and then poured onto ice water. The crystalline product was filtered off with suction, washed with water and recrystallized from dimethylformamide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07138398B2 |
| Source dataset | uspto-grants-2006_11 |
| ORD ID | ord-a41c70cf011b463e89063373069200fe |
| Source note | uspto-grants-2006_11 |