HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(4-Methyl-1,4-diazepan-1-yl)aniline → 6-Cyclopropylethynyl-3-[4-(4-methyl[1,4]diazepan-1-yl)phenyl]-3H-thieno[3,2-d]pyrimidin-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(4-Methyl-1,4-diazepan-1-yl)aniline | HCID 13007951 | — |
| Reactant | 5-Cyclopropylethynyl-3-(dimethylaminomethyleneamino)thiophene-2-carboxylic acid methyl ester | HCID 68944348 | — |
| Product | 6-Cyclopropylethynyl-3-[4-(4-methyl[1,4]diazepan-1-yl)phenyl]-3H-thieno[3,2-d]pyrimidin-4-one | HCID 57625318 | — |
Reaction Steps
5-Cyclopropylethynyl-3-(dimethylaminomethyleneamino)thiophene-2-carboxylic acid methyl ester was reacted with 4-(4-methyl[1,4]diazepan-1-yl)phenylamine by method A1. The product with the molecular weight of 404.53 (C23H24N4OS) was obtained in this way; MS (ESI): 405 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08828991B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-f2d3ec1f9e6d4b2c8647a68d55357d04 |
| Source note | uspto-grants-2014_09 |