HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-3-nitro-5-(2-phenylethyl)-pyridine → 2,3-Diamino-5-(2-phenylethyl)pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-3-nitro-5-(2-phenylethyl)-pyridine | HCID 21882748 | — |
| Solvent | Dichloromethane methanol | HCID 21226129 | — |
| Product | 2,3-Diamino-5-(2-phenylethyl)pyridine | HCID 21882738 | — |
| Product | 2-Amino-3-nitro-5-(2-phenylethyl)-pyridine | HCID 21882748 | — |
Reaction Steps
Similiarly to Example C1, the hydrogenation of 0.92 g of 2-amino-3-nitro-5-(2-phenylethyl)-pyridine (starting material F2) gives 0.76 g of the title compound as a tan powder of m.p. 87–88° C. (after chromatography with dichloromethane/methanol 30:1). The mass spectrum shows the molecular peak MH+ at 214.3 Da.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07138399B2 |
| Source dataset | uspto-grants-2006_11 |
| ORD ID | ord-8d07c7c485a3498780db4d2626a2ea55 |
| Source note | uspto-grants-2006_11 |