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HRID722151

反应详情

EQUATION

反应方程式

HRID 722151 的结构方程式

REACTANTS

反应物

3
结构：CCN(CC)CC
HCID8471

Triethylamine

C6H15N

结构：COC(=O)CC(=O)Cl
HCID123460

Methyl 3-chloro-3-oxopropionate

C4H5ClO3

结构：Nc1cnccc1C(=O)O
HCID459531

未命名化合物

PRODUCTS

生成物

1
结构：COC(=O)CC(=O)Nc1cnccc1C(=O)O
HCID12988781

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CC(C)=O
溶剂HCID180

Acetone

C3H6O

PROCEDURE

实验过程

A solution of 3-aminopyridine-4-carboxylic acid (1.0 eq), methyl 2-(chlorocarbonyl)acetate (1.1 eq), and triethylamine (2.0 eq) in acetone was stirred overnight at room temperature. The solvent was removed in vacuo. The product was used without further purification. LC/MS m/z 239.2 (MH+), Rt 1.40 minutes.

WORKUP

后处理

  1. customThe solvent was removed in vacuo
  2. customThe product was used without further purification