Sodium Hydroxide → HCID 178488183, compound

HRID 722204Notes

Reaction equation

HRID 722204 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([C:12]2[NH:13][C:14]([CH2:17][C:18]([O:20]CC)=[O:19])=[N:15][N:16]=2)[CH:6]=[CH:7][C:8]=1[N+:9]([O-:11])=[O:10].[OH-].[Na+]>CO>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([C:12]2[NH:13][C:14]([CH2:17][C:18]([OH:20])=[O:19])=[N:15][N:16]=2)[CH:6]=[CH:7][C:8]=1[N+:9]([O-:11])=[O:10]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 178470789HCID 178470789, compound

Product 1

HCID 178488183HCID 178488183, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The mixture of 140 mg of ethyl [5-(3-methoxy-4-nitrophenyl)-4H-[1,2,4]triazol-3-yl]acetate, 5 ml of methanol and 1 ml of 1N sodium hydroxide was stirred at room temperature for 2 hours. Afterwards, the volatile fractions are removed on a rotary evaporator, the residue is diluted with 10 ml of water and adjusted to pH 5 using 1N hydrochloric acid. The solid was filtered off with suction after the stirring.

Workup

  1. customAfterwards, the volatile fractions are removed on a rotary evaporator
  2. additionthe residue is diluted with 10 ml of water
  3. filtrationThe solid was filtered off with suction after the stirring

Sources & evidence

ORD record
ord-b3f705ec3fb846679e7edcc61372e661
Source dataset
uspto-grants-2006_11
Patent number
US07138414B2

Reaction notes

Loading…