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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 722207Generated: October 25, 2026

2-(3-Methyl-5-(2-nitrophenyl)-4H-1,2,4-triazol-4-yl)benzoic acid → 2-(3-(2-Aminophenyl)-5-methyl-4H-1,2,4-triazol-4-yl)benzoic acid

https://huagongshe.com/reaction/722207

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(3-Methyl-5-(2-nitrophenyl)-4H-1,2,4-triazol-4-yl)benzoic acidHCID 21883887—
CatalystPalladiumHCID 23938—
SolventTetrahydrofuranHCID 8028—
Product2-(3-(2-Aminophenyl)-5-methyl-4H-1,2,4-triazol-4-yl)benzoic acidHCID 21883868—

Reaction Steps

was prepared by hydrogenating 400 mg of 2-[3-methyl-5-(2-nitrophenyl)-[1,2,4]triazol-4-yl]benzoic acid in the presence of Pd/C in tetrahydrofuran and purified by stirring with dichloromethane.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07138414B2
Source datasetuspto-grants-2006_11
ORD IDord-197ab0f37be24bf0b716e4cde269af23
Source noteuspto-grants-2006_11