反应详情

Hydrogen was introduced under atmospheric pressure into the mixture of 350 mg of 5-methyl-2-(3-methyl-4-nitrophenyl)-1,2-dihydropyrazol-3-one, 70 mg of Pd/C and 50 ml of tetrahydrofuran until the theoretical uptake. Afterwards, the catalyst was filtered off with suction and the mixture was concentrated to dryness under reduced pressure and the residue was stirred in t-butyl methyl ether. The solid was filtered off with suction and dried under reduced pressure.

1. filtrationAfterwards, the catalyst was filtered off with suction
2. concentrationthe mixture was concentrated to dryness under reduced pressure
3. filtrationThe solid was filtered off with suction
4. customdried under reduced pressure