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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 72227Generated: October 30, 2026

Sodium borohydride → 6-[Hydroxy(tetrahydropyran-4-yl)methyl]-3-[4-(4-methyl[1,4]diazepan-1-yl)phenyl]-3H-thieno[3,2-d]pyrimidin-4-one

https://huagongshe.com/reaction/72227

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium borohydrideHCID 4311764—
ReactantHCID 24859572HCID 24859572—
Product6-[Hydroxy(tetrahydropyran-4-yl)methyl]-3-[4-(4-methyl[1,4]diazepan-1-yl)phenyl]-3H-thieno[3,2-d]pyrimidin-4-oneHCID 24859707—

Reaction Steps

3-[4-(4-Methyl[1,4]diazepan-1-yl)phenyl]-6-(tetrahydropyran-4-carbonyl)-3H-thieno[3,2-d]pyrimidin-4-one and sodium borohydride were reacted by method Y. The product with the molecular weight of 454.60 (C24H30N4O3S) was obtained in this way; MS (ESI): 455 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08828991B2
Source datasetuspto-grants-2014_09
ORD IDord-05bf72ce54b042e0a9244af8981919c9
Source noteuspto-grants-2014_09