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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 72229Generated: October 29, 2026

Dimethylformamide dimethyl acetal → 3-(Dimethylaminomethyleneamino)-5-isobutyrylthiophene-2-carboxylic acid methyl ester

https://huagongshe.com/reaction/72229

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamide dimethyl acetalHCID 78373—
ReactantHCID 68977753HCID 68977753—
Product3-(Dimethylaminomethyleneamino)-5-isobutyrylthiophene-2-carboxylic acid methyl esterHCID 68977174—

Reaction Steps

3-Amino-5-isobutyrylthiophene-2-carboxylic acid methyl ester and dimethoxymethyldimethylamine were reacted by method B. The product with the molecular weight of 382.36 (C13H18N2O3S) was obtained in this way; MS (ESI): 383 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08828991B2
Source datasetuspto-grants-2014_09
ORD IDord-c0f84c2ef1e549adabe5964b9fd7e731
Source noteuspto-grants-2014_09