Dimethylformamide dimethyl acetal → 3-(Dimethylaminomethyleneamino)-5-isobutyrylthiophene-2-carboxylic acid methyl ester

HRID 72229Notes

Reaction equation

HRID 72229 reaction equation
[CH3:1][O:2][C:3]([C:5]1[S:6][C:7]([C:11](=[O:15])[CH:12]([CH3:14])[CH3:13])=[CH:8][C:9]=1[NH2:10])=[O:4].CO[CH:18]([N:21]([CH3:23])[CH3:22])OC>>[CH3:1][O:2][C:3]([C:5]1[S:6][C:7]([C:11](=[O:15])[CH:12]([CH3:13])[CH3:14])=[CH:8][C:9]=1[N:10]=[CH:18][N:21]([CH3:23])[CH3:22])=[O:4]

Participants

3

Reactant 2

HCID 78373Dimethylformamide dimethyl acetalHCID 68977753HCID 68977753, compound

Product 1

HCID 689771743-(Dimethylaminomethyleneamino)-5-isobutyrylthiophene-2-carboxylic acid methyl ester

Procedure

3-Amino-5-isobutyrylthiophene-2-carboxylic acid methyl ester and dimethoxymethyldimethylamine were reacted by method B. The product with the molecular weight of 382.36 (C13H18N2O3S) was obtained in this way; MS (ESI): 383 (M+H+).

Workup

  1. customThe product with the molecular weight of 382.36 (C13H18N2O3S) was obtained in this way

Sources & evidence

ORD record
ord-c0f84c2ef1e549adabe5964b9fd7e731
Source dataset
uspto-grants-2014_09
Patent number
US08828991B2

Reaction notes

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