HuagongsheHuagongshe Chemistry Print Report · For research reference only
p-Toluenesulfonic acid → 3-[4-(4-Methyl[1,4]diazepan-1-yl)phenyl]-6-(2-methylpropenyl)-3H-thieno[3,2-d]pyrimidin-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | p-Toluenesulfonic acid | HCID 6101 | — |
| Reactant | HCID 24859708 | HCID 24859708 | — |
| Product | 3-[4-(4-Methyl[1,4]diazepan-1-yl)phenyl]-6-(2-methylpropenyl)-3H-thieno[3,2-d]pyrimidin-4-one | HCID 24859846 | — |
Reaction Steps
6-(1-Hydroxy-2-methylpropyl)-3-[4-(4-methyl[1,4]diazepan-1-yl)phenyl]-3H-thieno[3,2-d]pyrimidin-4-one and p-toluenesulfonic acid were reacted by method AA. The crude product was purified by preparative HPLC. The product with the molecular weight of 394.54 (C22H26N4OS) was obtained in this way; MS (ESI): 395 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08828991B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-83be697aa64b478d8d28e3e38497437c |
| Source note | uspto-grants-2014_09 |