化工社化工社 化学情報印刷レポート · 研究参考用
1-(4-aminophenyl)-N,N-dimethylpyrrolidin-3-amine → 6-(tert-Butyl-diphenyl-silanyloxymethyl)-3-[4-(3-dimethylamino-pyrrolidin-1-yl)-phenyl]-3H-thieno[3,2-d]pyrimidin-4-one
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1-(4-aminophenyl)-N,N-dimethylpyrrolidin-3-amine | HCID 21916591 | — |
| 反応物 | HCID 131731827 | HCID 131731827 | — |
| 生成物 | 6-(tert-Butyl-diphenyl-silanyloxymethyl)-3-[4-(3-dimethylamino-pyrrolidin-1-yl)-phenyl]-3H-thieno[3,2-d]pyrimidin-4-one | HCID 131731826 | — |
反応手順
5-(tert-Butyl-diphenyl-silanyloxymethyl)-3-(dimethylamino-methyleneamino)-thiophene-2-carboxylic acid methyl ester was reacted with [1-(4-Amino-phenyl)-pyrrolidin-3-yl]-dimethyl-amine by method A1. The product with the molecular weight of 608.87 (C35H40N4O2SSi) was obtained in this way; MS (ESI): 609 (M+H+).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08828991B2 |
| 出典データセット | uspto-grants-2014_09 |
| ORD ID | ord-00ebf7734d8f40c79d0e8437fbdbe257 |
| 出典メモ | uspto-grants-2014_09 |