3-Aminobenzoic Acid → 292644-37-2

HRID 722472Notes

Reaction equation

HRID 722472 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([CH3:8])=[CH:4][C:3]=1[OH:9].[NH2:10][C:11]1[CH:12]=[C:13]([CH:17]=[CH:18][CH:19]=1)[C:14](O)=O>>[NH2:10][C:11]1[CH:12]=[C:13]([C:14]2[O:9][C:3]3[CH:4]=[C:5]([CH3:8])[CH:6]=[CH:7][C:2]=3[N:1]=2)[CH:17]=[CH:18][CH:19]=1

Participants

3

Reactant 2

HCID 74193-Aminobenzoic AcidHCID 760822-Amino-5-methylphenol

Product 1

HCID 721026292644-37-2

Procedure

Prepared by the method of Example 1a), from 2-amino-5-methylphenol (448 mg, 3.6 mmol) and 3-aminobenzoic acid (500 mg, 3.6 mmol) the subtitle compound was obtained, 97 mg (12%). 1H NMR (CDCl3) δ 7.55(d, J=8.2 Hz, 2H), 7.49(t, J=1.9 Hz, 1H), 7.30(s, 1H), 7.22(t, J=7.5 Hz, 1H), 7.08(dd, J=1.1, 8.2 Hz, 1H), 6.76(dd, J=2.3, 7.9 Hz, 1H), 2.43(s, 3H). MS 225 m/z (M+H)+.

Sources & evidence

ORD record
ord-40ccac82d75343f8bcdaec9d7d2d597e
Source dataset
uspto-grants-2006_11
Patent number
US07138425B2

Reaction notes

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