HuagongsheHuagongshe Chemistry Print Report · For research reference only
Oxalyl chloride → 4-Methoxy-3-nitrobenzoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | 4-Methoxy-3-nitrobenzoic acid | HCID 66640 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 4-Methoxy-3-nitrobenzoyl chloride | HCID 12375463 | — |
Reaction Steps
Oxalyl chloride (15.8 ml, 180 mmol) was added dropwise with stirring to a solution of 4-methoxy-3-nitrobenzoic acid (7.00 g, 36.00 mmol) in THF containing 10 μL DMF. After 1 h the solvent was removed under reduced pressure. The product was used directly in the next step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07138425B2 |
| Source dataset | uspto-grants-2006_11 |
| ORD ID | ord-78d80d48ad5e4408834a0a40c6d6770a |
| Source note | uspto-grants-2006_11 |