3-Acetylphenylboronic acid → HCID 21884534, compound

HRID 722495Notes

Reaction equation

HRID 722495 reaction equation
[N+:1]([C:4]1[CH:5]=[C:6]([C:12]2[O:13][C:14]3[CH:20]=[CH:19][C:18](Br)=[CH:17][C:15]=3[N:16]=2)[CH:7]=[CH:8][C:9]=1[O:10][CH3:11])([O-:3])=[O:2].[C:22]([C:25]1[CH:26]=[C:27](B(O)O)[CH:28]=[CH:29][CH:30]=1)(=[O:24])[CH3:23]>>[N+:1]([C:4]1[CH:5]=[C:6]([C:12]2[O:13][C:14]3[CH:20]=[CH:19][C:18]([C:29]4[CH:28]=[CH:27][CH:26]=[C:25]([C:22](=[O:24])[CH3:23])[CH:30]=4)=[CH:17][C:15]=3[N:16]=2)[CH:7]=[CH:8][C:9]=1[O:10][CH3:11])([O-:3])=[O:2]

Participants

3

Reactant 2

HCID 27343103-Acetylphenylboronic acidHCID 218843422-(3-Nitro-4-methoxyphenyl)-5-bromobenzoxazole

Product 1

HCID 21884534HCID 21884534, compound

Procedure

Prepared by the method of Example 15d), from 2-(3-nitro-4-methoxyphenyl)-5-bromobenzoxazole (200 mg, 0.57 mmol) and 3-acetylphenylboronic acid (139 mg, 0.85 mmol) the subtitle compound was obtained (89 mg, 26%). 1H NMR (DMSO) δ 8.75(d, 1H), 8.46(dd, 1H), 8.23(t, 1H), 7.98–7.96(m, 2H), 7.69–7.56(m, 3H), 7.27(d, 1H), 4.08(s, 3H), 2.68(s, 3H).

Sources & evidence

ORD record
ord-f92c68b4abfd44f093514d5461e0f31d
Source dataset
uspto-grants-2006_11
Patent number
US07138425B2

Reaction notes

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