2,4-Difluorophenylboronic acid → HCID 21884579, compound

Participants

Reaction Steps

Prepared by the method of Example 15d), from 2-(3-nitro-4-methoxyphenyl)-5-bromobenzoxazole (200 mg, 0.57 mmol) and 2,4-difluorophenylboronic acid (136 mg, 0.86 mmol) the subtitle compound was obtained, (57 mg, 26%). 1H NMR (DMSO) δ 8.71(d, 1H), 8.53(dd, 1H), 8.01(s, 1H), 7.97(d, 1H), 7.70(m, 3H), 7.48(dt, 1H), 7.30(dt, 1H), 4.12(s, 3H). MS 383 m/z (M+H)+.

Provenance & Evidence