2-(2-Fluoro-5-nitrophenyl)-5-phenylbenzoxazole → HCID 21884372, compound

HRID 722527Notes

Reaction equation

HRID 722527 reaction equation
F[C:2]1[CH:7]=[CH:6][C:5]([N+:8]([O-:10])=[O:9])=[CH:4][C:3]=1[C:11]1[O:12][C:13]2[CH:19]=[CH:18][C:17]([C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=3)=[CH:16][C:14]=2[N:15]=1>C(O)CCC>[N+:8]([C:5]1[CH:6]=[CH:7][C:2]([O:12][CH2:11][CH2:3][CH2:2][CH3:7])=[C:3]([C:11]2[O:12][C:13]3[CH:19]=[CH:18][C:17]([C:20]4[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=4)=[CH:16][C:14]=3[N:15]=2)[CH:4]=1)([O-:10])=[O:9]

Participants

3

Reactant 1

HCID 218843342-(2-Fluoro-5-nitrophenyl)-5-phenylbenzoxazole

Product 1

HCID 21884372HCID 21884372, compound

Reagents, catalysts & solvents 1

HCID 2631-ButanolSolvent

Procedure

Prepared by the method of Example 44a), from 2-(2-fluoro-5-nitrophenyl)-5-phenylbenzoxazole (200 mg, 0.6 mmol) in butanol (2 ml) the subtitle compound was obtained (195 mg, 87%). 1H NMR (DMSO) δ 8.87(d, 1H), 8.45(dd, 1H), 8.08(d, 1H), 7.85(d, 1H), 7.70(m, 3H), 7.51(t, 3H), 7.40(t, 1H), 4.35(t, 2H), 1.83(q, 2H), 1.57(m, 2H), 1.01(t, 3H).

Sources & evidence

ORD record
ord-06ada23d45b041819de4240fda581d1c
Source dataset
uspto-grants-2006_11
Patent number
US07138425B2

Reaction notes

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