HuagongsheHuagongshe Chemistry Print Report · For research reference only
p-Toluenesulfonic acid monohydrate → 2-(3-Nitro-6-fluorophenyl)-5-methoxybenzoxazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | p-Toluenesulfonic acid monohydrate | HCID 521998 | — |
| Reactant | N-(2-Hydroxy-5-methoxyphenyl)-2-fluoro-5-nitrobenzamide | HCID 21884380 | — |
| Product | 2-(3-Nitro-6-fluorophenyl)-5-methoxybenzoxazole | HCID 21884462 | — |
Reaction Steps
Prepared by the method of Example 15b), from N-(2-hydroxy-5-methoxyphenyl)-2-fluoro-5-nitro benzamide (1.23 g, 4.0 mmol) and p-toluenesulfonic acid monohydrate (1.67 g, 8.8 mmol) the subtitle compound was obtained (700 mg, 53%). MS 289.1 m/z (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07138425B2 |
| Source dataset | uspto-grants-2006_11 |
| ORD ID | ord-77133f164a8f436e9c0648aaf06d5fc2 |
| Source note | uspto-grants-2006_11 |