p-Toluenesulfonic acid monohydrate → HCID 21884462, compound

HRID 722574Notes

Reaction equation

HRID 722574 reaction equation
O[C:2]1[CH:7]=[CH:6][C:5]([O:8][CH3:9])=[CH:4][C:3]=1[NH:10][C:11](=[O:22])[C:12]1[CH:17]=[C:16]([N+:18]([O-:20])=[O:19])[CH:15]=[CH:14][C:13]=1[F:21].O.C1(C)C=CC(S(O)(=O)=O)=CC=1>>[N+:18]([C:16]1[CH:17]=[C:12]([C:11]2[O:22][C:2]3[CH:7]=[CH:6][C:5]([O:8][CH3:9])=[CH:4][C:3]=3[N:10]=2)[C:13]([F:21])=[CH:14][CH:15]=1)([O-:20])=[O:19]

Participants

3

Reactant 2

HCID 521998p-Toluenesulfonic acid monohydrateHCID 21884380N-(2-Hydroxy-5-methoxyphenyl)-2-fluoro-5-nitrobenzamide

Product 1

HCID 21884462HCID 21884462, compound

Procedure

Prepared by the method of Example 15b), from N-(2-hydroxy-5-methoxyphenyl)-2-fluoro-5-nitro benzamide (1.23 g, 4.0 mmol) and p-toluenesulfonic acid monohydrate (1.67 g, 8.8 mmol) the subtitle compound was obtained (700 mg, 53%). MS 289.1 m/z (M+H)+.

Sources & evidence

ORD record
ord-77133f164a8f436e9c0648aaf06d5fc2
Source dataset
uspto-grants-2006_11
Patent number
US07138425B2

Reaction notes

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